Growth Factors and Tumor Biology


We are interested in basic and clinical aspects of the progression of tumours of endocrine origin or of other cell lines, diagnosed in paediatric patients. We study the participation of the insulin-like growth factors (IGFs) system in the establishment and progression of tumours of the adrenal medulla (phaeochromocytomas) associated or not with genetic diseases, and in tumours of the Central Nervous System in paediatric patients, as well as its prognostic value in these pathologies.


Main projects

  1. Insulin-like growth factors (IGFs) system in central nervous system tumours in paediatric patients.
  2. Expression of IGF-1 receptor type 1 (IGF-1R) and brachyury transcription factor (brachy) in paediatric thyroid nodular disease: basic and clinical studies.
  3. Molecular markers in paediatric CNS tumours. Its importance as a diagnostic tool, prognostic value and therapeutic opportunity.



Dr Pennisi Patricia (contact:

Dr Fernandez María Celia (contact:

Dr  Martin Ayelen (contact:

MD Clément Florencia (contact:

Castro Julia (contact: